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This can make communication with others challenging

Despite undergoing negative selection only on VAMP1, X(PC) also lost activity on all other known native BoNT/X substrates, including VAMP4, VAMP5 and YKT6 (Fig

That convergence of independent findings across diverse research groups adds weight to the overall body of evidence in a way that designed peptides with narrower mechanistic rationales cannot replicate

While our study highlights the significance of hepsin in the context of liver protection and its potential therapeutic implications in APAP-induced hepatotoxicity, there are limitations to consider when evaluating hepsin as a candidate drug or therapeutic strategy

Glutathione participates in natural antioxidant and detoxification pathways