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The direct cardiovascular effects represent a combination of platelet inhibition, augmented fibrinolytic responses, and attenuated thrombogenesis that collectively address not only the prothrombotic phenotypes of DM mellitus, obesity, and chronic kidney disease but a novel prevention approach beyond traditional risk factors for myocardial infarction, ischemic stroke, and cardiovascular death [90, 91]

In this randomised clinical trial, participants were randomly assigned to standard of care or intensive multifactorial intervention that included intensive glycaemic and BP management, lipid-lowering therapy and antiplatelet therapy

Target Audience: This article is written for physicians, clinical researchers, and allied healthcare professionals seeking an advanced understanding of the therapeutic potential and safety considerations of BPC-157 and TB-500

doi: 10.1016/j.pneurobio.2010.07.003 25 LarsenPVrangNTang-ChristensenM