Bykova A, Serova M, Chashkina M et al (2024) Glucagon-like peptide-1 receptor agonists in the context of pathophysiology of diverse heart failure with preserved ejection fraction phenotypes: potential benefits and mechanisms of action
72 CAR T-cell therapy directly targets tumor surface antigens via engineered CARs, completely bypassing the tumor cell-intrinsic MHC class I antigen presentation pathway, whereas CAR-NK cell therapy integrates CAR-directed cytotoxicity with the innate missing-self recognition of NK cells, enabling efficient elimination of tumor cells with downregulated or absent MHC class I expression and thereby directly addressing resistance mechanisms
Additional trials of GLP-1 for addiction will add confidence, but there is already far more evidence of GLP-1 efficacy for addiction than mRNA vaccines had for COVID when Operation Warp Speed was launched
Another SHE Media member, Gina Vaynshteyn (AVP, Commerce), also started a GLP-1 program postpartum
Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy
