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A typical loading dose is 1,000 mcg (1 mg) administered intramuscularly several times per week (such as every other day or 3 times per week) for a couple of weeks
Several drugs, including colchicine, have been reported to reduce the absorption of methylcobalamin, vitamin B12
Always swirl gently
Its important to maintain realistic expectations
Due to inclusion of patients only with early-stage ALS, noninvasive or invasive ventilatory support and patient mortality did not occur during the 16-week trial period, rendering secondary endpoints ineffective
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