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With a projected net effect of around $18 billion in additional Medicare spending over a decade, our model shows that GLP-1 drugs still dont pay for themselves yet at the new price, Kim said

Safety notes: Contraindicated in individuals with active malignancy or elevated cancer risk, as TB-500's proangiogenic activity could theoretically promote tumor growth or metastasis

Lilly estimates that fewer than 1 in 10 Americans who could benefit from a GLP-1 treatment are currently using one and a pill with no dosing restrictions is part of their answer to that gap

Once considered a secondary benefit of diabetes drugs, significant and sustained weight loss is now a primary indication for this class of medication

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