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Afterward, the PBS, NP2, and NP4 solutions were bubbled with the flowing O 2 , where the O 2 concentration was monitored using a portable dissolved oxygen meter (Hanna S20 Instruments HI-2004-02 Edge Dissolved Oxygen Meter) for 5 min
10.1016/j.ecoenv.2021.113135 34
47,48 Moreover, active or inactive drug metabolites can influence both efficacy and adverse effects, as seen with prodrugs such as cyclophosphamide
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