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At 2.4 mg weekly, average weight loss reached about 15% over 68 weeks. Response varied widely: 86% lost at least 5%, 69% lost 10%, half lost 15%, and about one-third lost 20%. These results describe that cohort rather than a universal forecast

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Preclinical studies confirmed that adding glucagon activity helps counteract the bodys adaptive slowing of metabolism during weight loss [7]