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Exendin-4 ameliorates high glucose-induced fibrosis by inhibiting the secretion of miR-192 from injured renal tubular epithelial cells
In keloids, it disrupts the FOXO4-p53 interaction, inducing apoptosis in senescent fibroblasts and reducing pro-inflammatory and mesenchymal fibroblast subpopulations
In 1902, twenty years before insulin was discovered, other compounds from the gut, called incretins, were found to reduce blood sugar and affect other biological processes
That extinguisher is glutathione (GSH)
Community injectable users typically describe far smaller doses than the mouse-scaled equivalent
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