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31 , 11891205.e1113 (2020)

Traditional cell lines cannot adequately recapitulate intratumoral heterogeneity, whereas patient-derived organoids, xenografts, and ex vivo co-culture systems only partially reproduce immune, stromal, vascular, and microbial interactions

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The authors concluded that the evidence supports supplementation with collagen peptides and micronutrients as an effective treatment for antiaging effects in skincare [49]