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Nope to all of that, but its a marketing tactic I see literally every day with supplements
In pancreatic beta cells, GLP-1RA promotes the conversion of proinsulin to mature insulin by upregulating the expression of hormone converting enzymes PC1/3 and PC2, while reducing the proinsulin/insulin ratio and enhancing insulin biological activity
A big reason for these changes is the natural decline of certain compounds that our bodies produce in abundance when we're young
While the precise role of GIGYF1 in islet biology remains to be fully elucidated, functional studies point toward a potential role in beta cell stress responses and survival, especially under metabolic stress
10.1111/j.1365-3083.1989.tb01108.x 34
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