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26 Originating from the preproglucagon precursor, it is processed in intestinal L-cells to form GLP-1
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Most are self-administered injections taken weekly or daily
Recommended starting dose: Discontinue other basal insulin and/or GLP-1 agonist before initiating Soliqua Patients naive to basal insulin or a GLP-1 agonist, currently on a GLP-1 agonist or less than 30 units of basal insulin daily: starting dose is 15 units once daily Patients currently on 30 to 60 units of basal insulin daily, with or without a GLP-1 agonist: starting dose is 30 units once daily Maintenance: titrate dose up or down by 2 - 4 units every week based on blood sugar goals Missed doses: resume dosing at the next scheduled dose
Our view: Oral GLP-1 supplementation, combined with good nutrition and consistent habits, is the more evidence-supported non-prescription option
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