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Global analysis of the mitochondrial proteome in response to cellular GSH depletion To identify mitochondrial proteins regulated by GSH availability, we used quantitative proteomics and analyzed mitochondria immunopurified from HeLa cells expressing a mitotag (3XHA-OMP25-mCherry) grown in standard media or treated with the glutathione synthesis inhibitor, buthionine sulfoximine (BSO) 13
This study shows an association , not a proven cause-and-effect
Neither approach has been validated
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Compounded semaglutide contains the same active ingredient as both Wegovy and Ozempic, prepared by FDA-registered compounding pharmacies
