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Retatrutide: Complication Focus TRIUMPH-4: Obesity + knee osteoarthritis (445 participants) TRIUMPH-2: Obesity + type 2 diabetes TRIUMPH-6: Weight maintenance trial Advantage: Multiple complication-specific trials could lead to broader label (obesity + OA + OSA indications)
Glucagon-like peptide-1 receptor agonists and pancreatic cancer risk in patients with type 2 diabetes
Methylation is important for amino acid and hormone metabolism, detoxification, and epigenetics (adjusting gene function according to the environment)
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