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The 2-OH-E1 route catalyzed by CYP1A1 is a stable route, and it can be easily metabolized further through methylation, which is accomplished by catechol-O-methyltransferase (COMT)

Corticosteroid injections may actually impair long-term tendon health despite providing short-term pain relief

Further investigations are needed to better clarify this point, which is certainly of public health interest

Semaglutide, tirzepatide, and liraglutide are FDA-approved GLP-1 peptides that are clinically safe and effective for diabetes and weight management

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