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The fat cells themselves don't suddenly activate fat-storage pathways after two weeks without tirzepatide

The study also found that glutathione levels began to return to baseline approximately one month after supplementation ceased, indicating that consistent use is key to maintaining optimal levels

When combined with the reduced food intake from tirzepatide, carnitine levels could drop below optimal thresholds for efficient fat metabolism

Serious issues can also occur, such as infections or uneven fat removal

By significantly slowing the rate at which the stomach empties its contents, the medication may contribute to gastroesophageal reflux disease (GERD), which is listed as an adverse reaction in the Wegovy prescribing information