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1 2 3 4 5 6 7 8 9 "Lilly's oral GLP-1, orforglipron, demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines in successful Phase 3 trial" (Press release)
oral administration (less studied for musculoskeletal use) Typical dosing range: 200-500 mcg once or twice daily
This trial also stopped people abruptly and removed their lifestyle support at the same time, rather than tapering the dose gradually, which is closer to standard medical practice for many medications
Start with the protein portion and eat vegetables only if you have room
