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Common side effects of GLP-1R activation within the gastrointestinal tract also include nausea, vomiting, constipation, and diarrhea, due to the receptors role in modulating gastric emptying

Wang N, Tan AWK, Jahn LA, Hartline L, Patrie JT, Lin S, Barrett EJ, Aylor KW, Liu Z

This helps you feel full faster and eat less, but it also makes heavy or difficult-to-digest foods more likely to cause discomfort

9How Can Semaglutide Be Used During Lactation

Headaches have been reported by patients using Ozempic for weight loss and diabetes management, though they typically appear during the first few weeks of treatment