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In a mouse model of pancreatic cancer liver metastasis, the use of IGF-IR inhibitor IGF-Trap reshaped the local immunosuppressive microenvironment of liver tumors, reduced the recruitment of bone marrow-derived suppressor cells, reversed innate immune cell polarization and inhibited metastatic expansion
And oxidative stress may be one of the key drivers behind it
Keep in mind that most sugar substitutes are much sweeter than regular sugar, so start with a small amount and adjust to taste.
(0.03 MB DOC) Figure S7
It happens when your system is flooded with damaging molecules, known as free radicals, overwhelming your body's natural antioxidant defences
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