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Somi Javaid, MD, is a board-certified OB/GYN, a leading womens sexual health and menopause advocate and the founder of HerMD, a comprehensive womens health practice revolutionizing the future of womens healthcare
Research comparing mice treated with GLP-1 medications versus those on calorie restriction with similar weight loss showed the GLP-1 group had substantially greater reductions in liver fat 19
By promoting weight loss and improving metabolic health, GLP-1s may also indirectly reduce hot flash symptoms
& Brownell, K
In pancreatic cells, GLP-1 binds GLP-1R to promote the conversion of ATP into cytoplasmic cAMP, further activating the intracellular PKA/AMPK signaling pathway and promoting glucose-stimulated insulin secretion (GSIS) (Kahn, 2001)
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