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As a negative control, sensor chips were treated as described above in the absence of immobilized Tb TR

At week 4, women in the treatment group displayed improved skin elasticity (+12.7%), reduced wrinkle volume (16.5%), decreased transepidermal water loss (10.8%), increased hydration (+3.5%), and enhanced collagen density compared with baseline values (measured via specialized skin analysis instrumentation)

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Beneficial effects of multi-micronutrient supplementation with collagen peptides on global wrinkles, skin elasticity and appearance in healthy female subjects