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NO system dependence of atropine-induced mydriasis and L-NAME- and L-arginine-induced [PMID: 26698393] Laboratory literature summary: NO system dependence of atropine-induced mydriasis and L-NAME- and L-arginine-induced miosis: Reversal by the pentadecapeptide BPC 157
The kidney is the primary excretory organ for platinum-based agents and their metabolites, with the vast majority of the agents ultimately excreted via urine
mTORC1, via S6K1, also improves the translation of c-MYC and, in turn, inhibits the transcription of miR-23a and miR-23b, which post-transcriptionally repress GLS (Gao et al., 2009)
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NHS guidance describes an initial phase that can be every other day for 2 weeks (or until symptoms improve).Maintenance schedules are often every 23 months in appropriate long-term cases
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