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doi: 10.1016/j.ccell.2022.01.001 Summary Keywords metabolism, cancer, T cells, macrophages, immunotherapy, tumor microenvironment, angiogenesis Citation Wik JA, Berge ER, Stromsnes K and Sklhegg BS (2025) Metabolism in the tumor microenvironment: implications for pathogenesis and therapeutics

Elevated glycolysis and GLUTs, on the one hand, significantly increase energy supply in cancer cells and, on the other hand, enhance cancer cells survival ability in an oxygen-deprived environment, which finally exacerbates the progression of PDA

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