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The exclusion criteria were: females who were pregnant or experiencing a menstrual period, type 2 diabetes treated using an insulin regimen, malignancy, hematopathy, active tuberculosis, peptic ulcer with gastric bleeding, binge-eating disorder, psychiatric disease, congestive heart failure, clinically relevant renal or hepatic insufficiency, unstable coronary artery disease, cancer or a history of cancer

Hold the needle in place, push down on the plunger, and insert all of the solution

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Snchez-Snchez AM, Martn V, Garca-Santos G, Rodrguez-Blanco J, Casado-Zapico S, Suarez-Garnacho S, Antoln I, Rodriguez C (2011) Intracellular redox state as determinant for melatonin antiproliferative vs cytotoxic effects in cancer cells