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Food and Drug Administration (FDA) and/or have been proven to achieve certain therapeutic results or effects are likely to be false and violate Section 43(a) of the Lanham Act, 15 U.S.C
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In some particular embodiments of the present invention, Alloc in the Fmoc-Lys(Alloc)-OH in the preparation method is removed twice with 5-10 equivalents of morpholine (or 5-10 equivalents of phenylsilane as an alternative thereof) and 0.1-0.3 equivalents of Pd(PPh 3 ) 4 for 10-30 min each time, wherein CH 2 Cl 2 is used as a solvent in the removal
This feature enables them to effectively control the respective constitution and surface properties, resulting in improved drug loading, targeting capabilities and higher solubility of the drugs [160]
Additional pathologies beyond amyloidosis in mice increase similarity to AD The 5xFAD and NLGF mouse models of amyloidosis fail to capture the entire spectrum of AD-related proteomic changes
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