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Tumors with inherited or somatic deficiencies in HRR genes, such as BRCA1, BRCA2, PALB2, and RAD51, exhibit synthetic lethality to PARPis, including olaparib, rucaparib, niraparib, and talazoparib, which have shown durable efficacy in BRCA-mutant breast, ovarian, and prostate cancers
M.ChaudharyN.ChabenneJ
Find out more about UV and skin cancer, and how to stay safe in the sun
Acta 102 PochiniL.ScaliseM.IndiveriC
BPC 157 is a peptide originally derived from a protein in the stomach
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