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IV administration achieves serum concentrations not reliably achievable through oral supplementation, as oral glutathione is largely broken down in the digestive tract

12,13,37 However, current single-cell technologie still struggle to fully capture the native tissue architecture, while the sensitivity and specificity of liquid biopsies require further optimization

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The primary clinical evidence comes from a Phase II trial for postoperative ileus using 0.01-0.1 mg/kg IV with excellent tolerability (Barlind et al., 2008)