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As of 2023, no GLP-1 transdermal systems have completed Phase 3 clinical trials or received regulatory approval
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These warnings do not mean serious events are common
Most are gastrointestinal and usually mild: Nausea (often improves after 24 weeks) Diarrhea or constipation Bloating or abdominal discomfort Reduced appetite (that one's the point) Fatigue in the first few weeks To minimize them: follow the titration schedule, eat smaller meals, go easy on greasy/high-fat foods, stay hydrated, and consider injecting at bedtime
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