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The capacity of uric acid to neutralize reactive oxygen species (ROS) and shield neurons from oxidative damage may underlie its observed neuroprotective effects
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Our goal was to focus on how mitochondria facilitate the acute stress response to 5FU in cells that tolerated treatment (that is, were not sensitive enough to treatment to die)
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GSH is at 110 mM concentrations in all mammalian tissues (highest concentration in liver) as the most abundant non-protein thiol that protects against excessive oxidative stress
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