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human bioavailability is unknown Subcutaneous injection Human subcutaneous bioavailability and pharmacokinetics are unknown Factor Convenience Oral capsules No mixing or syringe math Subcutaneous injection Requires reconstitution, sterile supplies, and injection-site planning Factor Evidence limits Oral capsules No controlled human dose, benefit, or safety trial Subcutaneous injection No controlled human dose, benefit, or safety trial Factor Can the amounts be treated as equal

Immediate medical review is necessary for these signs, and therapy should be paused until a clinician evaluates the cause

Category 2 designation means the substance presents "safety concerns" and is prohibited from being used in compounding by licensed pharmacies