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In rats, the drugs, known as glucagon-like-peptide-1 (GLP-1) receptor agonists, have been shown to cause thyroid C-cell tumors
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On the latter, studies conducted using site-specific brain micro-injections and single-photon emission computed tomography documented a novel regulatory role of the hypothalamic supramammillary nucleus in the regulation of food intake and reward, posing this brain area as one of the main targets of the GLP1/E conjugate, along with the lateral hypothalamus and the nucleus of the solitary tract, whose activation may be responsible for the anorectic, weight-lowering and reward reducing effects of this multi-agonist 51
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Chemical properties Chemical Name: L--glutamyl-L-cysteinyl-glycine Molecular Formula: C10H17N3O6S CAS: 70-18-8 (reduced form) Molecular Weight: 307.32 g/mol Biological Significance Antioxidant Protection In our daily lives, the body constantly produces reactive oxygen species (ROS) and free radicals, which attack cell membranes, proteins, and DNA, causing oxidative stress, accelerating aging, or triggering diseases
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