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Why does tirzepatide cause diarrhea at higher doses? Tirzepatide diarrhea is dose-dependent because higher doses activate more GLP-1 and GIP receptors in the intestinal tract, amplifying the effects on gastric emptying, small bowel transit time, and fluid secretion into the gut lumen
Correlating the global signal with the time series of each voxel (Pearsons correlation) yields a whole-brain correlation, which is also considered a weighted form of functional connectivity density [42]
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Steady-state levels are reached over the first several weeks, and most people are evaluating appetite and progress over months of consistent weekly use, not days
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