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BoNTs have been approved for diverse indications, including cosmetic procedures, movement disorders, chronic migraines, autonomic dysfunctions and ophthalmological conditions, by inducing paralysis in various muscles 26

Tendon and Ligament Repair Chronic tendon issues like tendonitis and ligament injuries, including ACL tears, can take weeks or months to improve

For background on the broader angiotensin IV / AT4 system the work was built on, see Wright and Harding 1995 (PMID 7768321) and Wright et al

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They can range from mild to moderate and may include cramping, bloating, or a rash, in case of overdose