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Both are clinically supported, but they work through entirely different mechanisms

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It is thought that atenolol's antihypertensive activity may be related to action on the central nervous system (CNS) or it's inhibition of the renin-aldosterone-angiotensin system rather than direct effects on the vasculature

It is a core component of an already FDA-approved commercial drug

It is a peptide studied mainly for cognitive and neuroprotective effects, and some research suggests it may also support mood and the brain's stress response