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Starting a GLP-1RA appears associated with reduced risk of incident alcohol use, and possibly reduced opioid, cocaine, and nicotine use
These medications are strictly contraindicated in individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), a rare genetic disorder, causing certain endocrine tumours to develop
This is not unique to Belmar's formulation
A post-hoc analysis of the SURMOUNT-5 trial found that 89.9% of participants treated with tirzepatide reverted to normoglycemia (normal blood sugar levels), compared to only 76.2% with semaglutide
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