International Urology and Nephrology 2016 48:8 (1305-1312)
Seven additional Phase 3 readouts expected through 2026: TRIUMPH-1 (obesity), TRIUMPH-2 (obesity + diabetes), TRIUMPH-3 (obesity + cardiovascular risk), SELECT-M (MASH), SLEEP (OSA), BACK PAIN, and a cardiovascular/renal outcomes readout
They also illustrate an important distinction: increasing a laboratory measure of glutathione is not automatically proof that supplementation prevents disease, improves longevity or produces a noticeable clinical benefit
amycretin has no CV data Conclusion# Amycretin represents the most exciting pipeline asset in obesity medicine, with 24.3% weight loss in early trials suggesting it could substantially exceed every approved treatment
Additionally, improvements in fibrosis may not directly translate to immediate clinical benefits, complicating the assessment of treatment efficacy