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Started at 2.5mg weekly, increased by 2.5mg every 4 weeks as tolerated
It could be speculated that this increased discontinuation rate vs all comparators, including GLP-1 RAs, may be possibly attributed to the severity of gastrointestinal adverse events experienced with tirzepatide 15 mg, considering that the incidence of gastrointestinal adverse events was similar between tirzepatide and GLP-1 RAs
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It found that substances that stimulate oxytocin release, including melanotan 2, can promote social bonding in these species [7]
