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Tumor-derived hydrogen sulfide, produced by cystathionine--synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer
The study included 67,841 patients taking semaglutide (75.6%), 15,661 taking tirzepatide (17.5%), and 6,216 taking liraglutide (6.9%)
Neurotoxicity of tryptophan metabolites
These include: Carbonated beverages , which introduce additional gas into the digestive system High-fat foods , which further slow gastric emptying beyond semaglutide's effect Foods that commonly produce gas , such as beans, lentils, cruciferous vegetables (broccoli, cabbage, Brussels sprouts), and certain artificial sweeteners Large amounts of fiber introduced suddenly , though adequate fiber intake remains important for overall digestive health Maintaining adequate hydration is essential, as it helps prevent constipation, which can worsen bloating