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The protein expression levels of tight junction associated protein-1 (ZO-1), Occludin, inflammatory factors interleukin (IL)-6, IL-1 and tumor necrosis factor (TNF)-, SIRT1, STAT3, p-STAT3, and retinoic acid receptor-related orphan receptor gamma t (RORt) were detected by Western blot
Clin Med 2016;16:247-53
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However, these frameworks do not by themselves imply that a digital biomarker is acceptable for diagnostic use or as a primary efficacy endpoint
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