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GPx7 likes to interact with the domain of PDI, and intramolecular cooperation between the two redox-active sites of PDI increases the activity of the Ero1/GPx7/PDI triplet, thereby promoting protein folding mechanisms (Wang et al., 2014) (Figure 6)
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Total cell surface HA (left), HS (middle), and CS (right) measured in A-498 cells treated or not with hyaluronidase (5 U/mL)
doi: 10.1039/D3RA06537E 91
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