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This is because both GLP-1 and GIP are incretin hormones, which are released by the gut after eating
However, only 10% of the oral selegiline dose is bioavailable, leading to the need of high, daily doses causing a long list of adverse effects [191]
Oui, et mme particulirement intressante
Back Deacon, DF, Johnsen, AH, Holst, JJ (March 1995) 'Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo', Journal Clinical Endocrinology Metabolism , 80/3, 952-7
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