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Preclinical evidence strongly indicates that BPC-157 modulates this critical signaling pathway, leading to a cascade of downstream effects essential for tissue repair (Sikiric et al., J Physiol Paris , 2012)

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After complete transection 5 mm proximal to calcaneal insertion, daily BPC-157 (10 g, 10 ng, or 10 pg per kg body weight) was administered starting 30 minutes post-surgery