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Remarkably, 2012 showed no proteolytic cleavage even after 48 h incubation, confirming the anticipated benefit of the hydrocarbon stapling moiety on chemical stability and resistance to proteases 32
Furthermore, polyphenols have shown promising effects in preserving intestinal and BBB integrity in MPTP-induced PD mouse models
Huang, X
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[6] Scientists working with test models also comment that IGF-1 may have a GH independent growth stimulating effect, which with respect to cartilage cells is possibly optimized by the synergistic action with GH
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