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Structure and function of plant protein-derived antihypertensive peptides

Proposed mechanisms include upregulation of growth-hormone-receptor expression in injured tissue, VEGF-driven angiogenesis, modulation of the nitric-oxide pathway in vascular endothelium, and activation of FAK-paxillin signaling

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Dose-response studies indicate that BPC-157 at 800 ng/kg produces near-complete ulcer healing with thick granulation tissue formation, demonstrating potent effects at remarkably low doses