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The combination produces additive effects through dual receptor engagement
In addition to oral l-carnitine, metformin was administered either intraperitoneally (ip, solubilized in 0.9% NaCl) at a concentration of 100 mg/kg of rat weight twice a day for 4 weeks in the l-carnitine + Metformin group [28]
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doi: 10.3389/fcimb.2024.1348713 173 PastreloMMDias RibeiroCCDuarteJWBioago GollckeAPArtigiani-NetoRRibeiroDAet al
Finally, we identify current research gaps and propose future directions toward harnessing AST for promoting cognitive resilience and delaying the progression of neurodegenerative disorders
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