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AARS1 promotes diabetic kidney disease through rewiring Akt and NF-B signaling to suppress autophagy and sustain inflammation
Other studies have shown that changes in certain factors can regulate the expression of HGF and c-Met to regulate the HGF/c-Met axis
Mitophagy inhibits amyloid- and tau pathology and reverses cognitive deficits in models of Alzheimer's disease
Changes in the redox state of cells by cystine/cysteine circuitry control the ROS levels, which modulates cellular signal transduction pathways involved in cell survival and resistance to chemotherapy
PMID 23036594
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