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and the noncanonical BAF (ncBAF) complex (which includes SMARCA4, and BRD9) 3

Building on these ideas, Aviv and Shay (2018) further hypothesized that lengthened telomeres may enhance the risk for disorders linked to increased proliferation rate, including cancer, while shortened telomeres can enhance the risk for pathologies related to a restricted cellular proliferation and tissue degeneration, such as atherosclerosis-associated cardiovascular disorders

It also has secondary applications related to cardiovascular and kidney health for eligible patients

mean acceleration of 20%) and shortened the lag time (mean reduction of 34%) relative to placebo

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