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Additionally, 41% of patients who used 8 mg retatrutide showed an improvement in blood pressure, and they had to discontinue at least one antihypertensive medication

Directly inhibits vessel growth rather than promoting it

Singh SP, Wishnok M, Keshive M, Deen WM, Tannenbaum SR

Preclinical studies have shown promising results, with GLP-1 agonists demonstrating the ability to protect cartilage and reduce inflammation in animal models of osteoarthritis

Chris Masterjohn wrote an excellent review of this study and proposes other interesting possibilities, including gender differences and vitamin deficiency issues