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Its important to understand that while headaches are common, they generally are not a sign of a serious condition
Firstly, under conditions of insulin resistance, such as obesity and type 2 diabetes, GIP promotes lipid deposition in subcutaneous adipocytes [48]
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For instance, administration must occur in a fasted state (at least 2-3 hours post-meal) because elevated insulin and blood glucose can significantly blunt the pituitarys response to secretagogues
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