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Since glucocorticoids are known to mediate inhibition of NF-kB (beneficially modulated by certain antioxidants such as thiols), adjunctive therapy with an effective thiol donor (e.g., NAC or SAMe) and vitamin E may optimize control of inflammatory mediator release and cell response as compared to pure immunomodulatory treatment or therapy limited to antioxidants

Kaiser Permanente

There were no side effects from the product that I noticed