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Fatigue can stem from inadequate protein intake, dehydration, poor sleep, or other factors unrelated to NAD+ levels
doi:10.1038/s41598-020-74022-y Lozic M, Stambolija V, Krezic I, et al
For example, Advan's foot traffic data shows McDonald's visit frequency to be 70% higher than Olive Garden's
Cephalalgia 35(14):12781286 Bathel A, Schweizer L, Stude P et al (2018) Increased thalamic glutamate/glutamine levels in migraineurs
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